1(Heterocyclyl),2,4,5-Tetrasubstituted Benzenes as Protoporphyrinogen-IX Oxidase Inhibiting Herbicides
نویسندگان
چکیده
It is well known that agrochemicals have played a important role in agricultural production that provided for about 700 million people during the past 50 years. At the same time, the increasing world population seems to be a major driving force for the need to enhance the output of food production. The agrochemical industry has been very successful in developing new herbicides and other agrochemicals. Herbicides are used widely in the world in protecting crops from undue competition from weeds (Price & Kelton, 2011).
منابع مشابه
Protoporphyrin Accumulation Induced by Peroxidizing Herbicides is Counteracted by Safeners
Peter Böger and Roswitha M iller Lehrstuhl für Physiologie und Biochemie der Pflanzen, Universität Konstanz, D-78434 Konstanz, Bundesrepublik Deutschland Z. Naturforsch. 49c, 775-780 (1994); received October 13, 1994 Peroxidizing Herbicides, Safeners, Protoporphyrin IX Accumulation, Protoporphyrinogen Oxidase, Mixed Function Oxidase A number of safeners like naphthalene-1,8-dicarboxylic acid an...
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Protoporphyrinogen IX oxidase (PPO), the last common enzyme of haem and chlorophyll biosynthesis, catalyses the oxidation of protoporphyrinogen IX to protoporphyrin IX. The membrane-embedded flavoprotein is the target of a large class of herbicides. In humans, a defect in PPO is responsible for the dominantly inherited disease variegate porphyria. Here we present the crystal structure of mitoch...
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Diphenyl ether herbicides induce an accumulation of protoporphyrin IX in plant tissues. By analogy to human porphyria, the accumulation could be attributed to decreased (Mg or Fe)-chelatase or protoporphyrinogen oxidase activities. Possible effects of acifluorfen-methyl on these enzymes were investigated in isolated corn (maize, Zea mays) etioplasts, potato (Solanum tuberosum) and mouse mitocho...
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Peter Böger and Ko Wakabayashi* Lehrstuhl für Physiologie und Biochemie der Pflanzen, Universität Konstanz, D-78434 Konstanz, Bundesrepublik Deutschland * Chair of Physiology and Biochemistry, Department of Agricultural Chemistry. Tamagawa University, Machida-shi. Tokyo 194. Japan Z. Naturforsch. 50c, 159-166 (1995); received December 19, 1994 Chlorophyll Biosynthesis, Herbicide Mode of Action....
متن کاملPurification and properties of protoporphyrinogen oxidase from the yeast Saccharomyces cerevisiae. Mitochondrial location and evidence for a precursor form of the protein.
Protoporphyrinogen oxidase, the molecular target of diphenylether-type herbicides, was purified to homogeneity from yeast mitochondrial membranes and found to be a 55-kDa polypeptide with a pI of 8.5 and a specific activity of 40,000 nmol of protoporphyrin/h/mg of protein at 30 degrees C. The Michaelis constant (Km) for protoporphyrinogen IX was 0.1 microM. Due to the high affinity of the enzym...
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